منابع مشابه
Vitamin D deficiency and autoimmune diseases
Epidemiological evidence indicates a significant association between vitamin D deficiency and an increased incidence of autoimmune diseases. The presence of vitamin D receptors in the cells of the immune system and the fact that several of these cells produce the vitamin D hormone suggested that vitamin D could have immunoregulatory properties, and now potent immunomudulatory activities on dend...
متن کاملVitamin D – the cure for autoimmune diseases
Multiple Sclerosis is treatable. Dr Coimbra and his local team of assistant doctors have successfully treated thousands of patients with multiple sclerosis, in many cases reaching a complete resolution of both symptoms and clinical parameters. His therapy essentially relies on one agent: high-dose Vitamin D. The effects are as dramatic as practically blind beginning to see again and people leav...
متن کاملVitamin D and Autoimmune Diseases: Is Vitamin D Receptor (VDR) Polymorphism the Culprit?
BACKGROUND Vitamin D deficiency is becoming an increasing problem worldwide. It should not be underestimated, not only due to the well-known consequences vitamin D deficiency has on bone health, but primarily because recent studies have shown how the biologically active form of vitamin D - 1,25(OH)2D - is involved in many biological processes, including immune system modulation. Moreover, the p...
متن کاملThe association of FokI and ApaI polymorphisms in vitamin D receptor gene with autoimmune thyroid diseases in the northwest of Iran
Background: Some genetic factors are involved in the etiology of Hashimoto thyroiditis and Graves’ disease as autoimmune thyroid diseases (AITDs). Effects of vitamin D receptor gene polymorphisms in AITDs development have already been investigated in some previous studies. However, no study has been done on the association between VDR FokI and ApaI polymorphisms and AITDs in an Iranian po...
متن کاملEpigenetics and Autoimmune Thyroid Diseases
Increasing evidence suggests that epigenetic modifications, including changes in DNA methylation, covalent modifications of histone tails, and gene silencing mediated by non-coding RNA molecules, play a substantial role in the pathogenesis of autoimmune disorders and might be seen as the result of environmental insults that trigger these conditions. Studies in cells and tissues of patients with...
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ژورنال
عنوان ژورنال: Cellular & Molecular Immunology
سال: 2011
ISSN: 1672-7681,2042-0226
DOI: 10.1038/cmi.2010.73